Publications

DENVAX IS NOT A DRUG OR STEM CELL THERAPY

IT IS MADE BY PATIENT’S OWN WHITE BLOOD CELLS COLLECTED FROM PERIPHERAL BLOOD

PUBLICATIONS

OUR PUBLICATIONS ON DENDRITIC CELL THERAPY

Hepatocellular carcinoma responds to dendritic cell therapy – case study on 14 patients treated from year 2005-2008

Jamal A. Khan and Sharmin Yaqin

Abstract: Dendritic cells (dc) are the master immune cells eliciting both arms of immunity. T cells are almost totally dependent on dc for their maturation. Naive t cells are transformed into committed t lymphocytes with the brief exposure of dc, and during this interaction the specific epitopic representation is guaranteed to pass to t cells. Hepatocellular carcinoma (HCC) is fairly resistant cancer not responding to chemotherapy or mabs. Life span and quality of life get hampered. We have treated 14 patients of HCC from the year 2005 to 2008. 7 patients responded to therapy with decrease of alfafetoprotein to half. These patients have survived on an average of 23 months with 2 patients living for 36 months. Dendritic cell therapy seems to be good option for HCC patients and a large trial is warranted.

Presented in ‘Cancer Immunology and Immunotherapy: Building on Success’ conference held in National Institute of Health, Bethesda, MD, USA on September 22-23, 2011.

Pilot studies proving efficacy of dendritic cell therapy to prevent relapse in patients of ovarian carcinoma.

J.A. Khan (Noida, India)

Paper Presented at UICC World Cancer Congress ’08

27-31 August 2008 Geneva, Switzerland

The Presentation
The Abstract
The Scientific Program

KHAN Jamal A., YAQIN Sharmin

Successful immunological treatment of gallbladder cancer in India-Case report

Journal of Zhejiang University SCIENCE B 2006 7(9):719-724

PMID: 16909473 [PubMed- Indexed for MEDLINE]

KHAN Jamal A.*, YAQIN Sharmin

Dendritic cell therapy with improved outcome in glioma multiforme-a case report

Journal of Zhejiang University SCIENCE B 2006 7(2):114-117

PMID: 16421966 [PubMed- Indexed for MEDLINE]

Mrs. Aruna Tyagi, one of our patients since 2007 was diagnosed of cancer CBD involving duodenum and pancreas and operated in 2006. She received chemotherapy and radiotherapy but developed chest wall metastasis in 2007. She was operated upon for the second time and put on Denvax therapy soon after. She is since then on Denvax therapy and is free of disease clinically as well as radiologically. She is regularly examined by doctors in Rajiv Gandhi Cancer Hospital, Delhi. Her PET CT done in February 2009 revealed disease free status. Since then she has not had any metastasis or recurrent disease. Her story was published in Mail Today Newspaper published from New Delhi on 28-4-2009. Click this link.

PMID: 16909473 Mail Today page 27 dated 28/4/2009

Seminar

presented by Dr. Jamal A. Khan in ICON held at TATA MEMORIAL CANCER HOSPITAL on 19th September 2009 at R.D. Choksi Auditorium, Mumbai.

List of Trials held on dendritic cells in different institutions world over

You can click the link above to download the list of trials done on dendritic cell therapy and immunotherapy and read about its efficacy.

Please note: This therapy is customized or tailor-made and therefore cannot be propagated as a pharmaceutical product. However, due to simple blood collection method, where patient’s presence is not required; we are able to deliver the product Denvax to patients situated in all corners of India and many neighbouring countries.